Welcome
Company Overview
Core Principles
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  Overview
What Is Optical Mapping?
MapSolver™
Comparative Genomics
Whole Genome Sequence Assembly
Strain Typing
Food Microbiology
Epidemiology / Food Safety
Bibliography
 
 
 
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OpGen: Company Overview

OpGen Incorporated is a privately held whole genome analysis company headquartered in Gaithersburg Maryland. The Company was founded in January 2002 by the Wisconsin Alumni Research Foundation (“WARF”) with the objectives of developing and commercializing products and services utilizing proprietary core Optical Mapping Technologies for high precision microbial analysis markets. Optical Mapping is a powerful technology uniquely designed to rapidly generate de novo, high-resolution, ordered, whole genome maps from single DNA molecules. Optical Mapping provides a comprehensive view of microbial, yeast, or fungal genomic architecture, in samples of pure isolates or mixtures. Intrinsic to the technology are significant advantages that include the generation of ordered, high resolution data, >100 restriction sites/mb, without the cost of whole genome DNA sequencing or the inherent biases found in existing methodologies. Additionally, OpGen’s proprietary MapSolver™ analysis software enables the user to have maximum functionality and flexibility for visualizing all genomic data. Optical Maps can be compared and explored to find similarities, differences, insertions, deletions, genetic modifications, mobile elements such as pathogenicity islands, and uniquely, novel discovery.

The Argus® Optical Mapping System was launched in 2010 and is in use today for the automated assembly and analysis of genomes at the world's most prestigious sequencing centers.

The Company currently resides in two locations, the corporate offices and commercial MapIt® laboratory are located in Gaithersburg, Maryland. Select development functions are located in Madison, Wisconsin.

Our Beginning

The Company began deploying the capability and utility of Optical Mapping Technology in Life Sciences Specialties where Customers are able to obtain MapIt® Optical Mapping Services for specific microbial projects on a by-quotation basis, worldwide. Applications include but are not limited to strain typing and epidemiology, sequence assembly and validation, and comparative genomics. These applications are utilized for a variety of purposes by diverse industries including clinical and food microbiology, food safety, epidemiology, pharmacology, microbial forensics, manufacturing quality control and applied research. Customers may order Optical Mapping Services by contacting Customer Support and discussing their specific project needs, sample preparation and transport requirements with a Customer Support Specialist.

Our Journey Forward…

OpGen's powerful technology dramatically improves the quality of data and time-to-results by providing sequence information from single molecules of DNA many times faster and less expensively than currently possible. Applications for assembling large genomes such as humans, plants and animals have been developed and are expected to be introduced in the second half of 2011. Improved DNA sequencing bioinformatics workflows and databases are also under development. We expect these products to enable the creation of a high value DNA sequence analysis diagnostics business.