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Home > Technology > Comparative Genomics

Technology: Comparative Genomics

Compare Microbial Genomes Rapidly and Cost-effectively

• Compare Optical Maps between related organisms and view differences and similarities
• Find genetic variation: insertions, deletions and other genetic modifications
• Track mobile elements: pathogenicity islands, phage, transposons
• Distinguish strains & determine genetic relatedness between multiple isolates via Map-based clustering

Multi-isolate comparisons reveal motifs associated with critical phenotypes such as Mec cassette variants conferring Methicillin resistance in S. aureus.

Directly compare maps of related isolates to locate novel differences other technologies miss, such as insertions (top panel, white segment) or deletions (bottom panel). Regions of similarity indicated in green.

 

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