OpGen Contact:
Judy Macemon
VP Marketing, OpGen, Inc.
(240) 813-1279

Findings Reveal Ability to Detect Structural Variations in Human Genomes, Providing Researchers with a New Tool to Investigate the Causes of Genetic Diseases

Gaithersburg, Md.—February 14, 2012— OpGen, Inc., a whole-genome analysis company developing and commercializing a complete suite of break-through products and services based on its proprietary Whole Genome Mapping technology, announced today a new application for whole human chromosome mapping that improves the completeness of human genomes and enables thorough analysis of a wide spectrum of structural variations. This novel application will allow researchers to investigate the causes of diseases such as autism and developmental disorders where structural variations are suspected but have not been observed due to the limitations of existing genomics analysis tools. OpGen will present findings demonstrating this expanded functionality at the 2012 Advances in Genome Biology and Technology (AGBT) meeting to be held in Marco Island, Florida, on February 15-18, 2012.
 

Preliminary results from a comparative genomics study using the company’s Whole Genome Mapping technology and Genome-Builder™ tool suite demonstrate the ability to efficiently and accurately order and orient large sequence scaffolds on a human genome de novo sequence project. The findings also demonstrate the ability to effectively construct complete high density physical maps of human chromosome arms and have detected structural variations between human individuals. The data will be presented in a poster session by Richard Moore, M.D., Ph.D., chief scientific officer of OpGen, on Friday, February 17 at 4:30 p.m.  
 

“The ability to detect structural variations and large scale genomic rearrangements using whole human chromosome mapping now enables researchers to better understand the markers and origins of inherited and somatic genetic diseases,” said George M. Church, Ph.D., professor of genetics at Harvard Medical School and director of the Center for Computational Genetics. “OpGen’s new technology is an exciting advance in the area of human genomics research and has the potential to lead to the development of new clinical diagnostic tests and companion therapeutics for patients.”
 

Structural variations in human chromosomes are known to cause some types of mental retardation, muscular dystrophy and certain cancers such as leukemia and lymphoma. However, very few tools exist today that can identify new structural variations that might be associated with human genetic diseases. Sequencing and array CGH are limited in the kinds of genetic information they can provide.  OpGen’s Whole Genome Mapping technology can detect structural variations including balanced rearrangements, inversions and translocations, which are very challenging to detect with current methods. 
 

“Many genetic diseases such as autism and certain types of cancers can’t be explained by genetic sequencing alone,” said Douglas White, chief executive officer at OpGen. “Until now, researchers have not had the tools necessary to correlate the order and orientation of genes within a chromosome to completely and accurately determine the structural variations. When combined with sequence data, OpGen’s Whole Genome Mapping technology provides scientists with a more complete view of human chromosomes. We look forward to launching this breakthrough application through our MapIt services in 2012.”

About OpGen, Inc.
OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company’s Argus^® Whole Genome Mapping System, GenomeBuilder™ and MapIt^® Services provide high resolution, whole genome maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. OpGen’s powerful technology dramatically improves the quality of data and time-to results by providing sequence information from single DNA molecules more rapidly and less expensively than previously possible. The company is dedicated to positively influencing individual healthcare outcomes, advancing scientific research and enhancing public health by delivering precise, actionable information and results to customers in the life science and healthcare communities. OpGen’s customers include leading genomic research centers, biodefense organizations, academic institutions, clinical research organizations and biotechnology companies. For more information, visit www.opgen.com.

OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company has developed a platform, The Argus® Whole Genome Mapping System and also offers MapIt™ Services that provide high resolution, whole genome restriction maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. This proprietary de novo technology is free from the limitations of gel, PCR and sequencing-based methodologies, and expansion of Whole Genome Mapping technologies to large genomes and clinical diagnostics is currently in development. OpGen’s customers include leading genomic research centers, biodefense organizations, leading genomic research centers, academic institutions, clinical research organizations and biotechnology companies. 

OpGen is committed to supporting our Customers as valued partners by creating long-term relationships and continually exceeding their expectations. OpGen employees have created the company’s success. As a result of that success, we are seeking individuals who enjoy a challenge and desire to be part of a team making a difference in healthcare outcomes.

Position Summary

 We are seeking a bioinformatics scientist with experience in genomics to join our bioinformatics group. Working in a team environment, this individual will provide support for analysis and development of new applications of Whole Genome Mapping technology in analysis of a wide spectrum of genomes, including human, other mammalians and plant genomes.

 Primary Job Functions

 The incumbent will provide bioinformatics support for Argus and MapIt service customers, participate in development of new applications, and contribute to other aspects of bioinformatics effort at OpGen. S/he will utilize existing analytical tools developed at OpGen, perform analysis on optical mapping data, generate analytical reports and communicate with scientists for interpretation of the results. As a member of the bioinformatics team, s/he will also provide valuable input for new application development, and participate in the development effort.

 Education/Skills/Attributes Required 

• Advanced degree in Genomics, Bioinformatics, or other related scientific/engineering fields (or equivalent professional experiences).
• Four to eight years of working experience in genomic data analysis and bioinformatics tool development, preferably in NGS.
• Hands on experience with bioinformatics tools and databases.
• Demonstrated ability to understand computational biology and bioinformatics concepts, and complex scientific algorithms.
• Software development experience, preferable in a team environment.
• Solid programming skills in C/C++, PERL, Java, and/or shell scripting in a Unix/Linux based system.
• Experience with high performance and cloud computing is desirable.
• Strong communication skills, with the ability to effectively articulate complex, technical information to customers and scientists.

Qualified applicants for the Bioinformatics Scientist position should submit a cover letter and resume to jobs@opgen.com indicating JOB CODE: BS in the subject heading.  Visit www.OpGen.com for a full listing of our open positions.  OpGen is an Equal Opportunity Employer.

OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company has developed a platform, The Argus® Whole Genome Mapping System and also offers MapIt™ Services that provide high resolution, whole genome restriction maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. This proprietary de novo technology is free from the limitations of gel, PCR and sequencing-based methodologies, and expansion of Whole Genome Mapping technologies to large genomes and clinical diagnostics is currently in development. OpGen’s customers include leading genomic research centers, biodefense organizations, leading genomic research centers, academic institutions, clinical research organizations and biotechnology companies. 

OpGen is committed to supporting our Customers as valued partners by creating long-term relationships and continually exceeding their expectations. OpGen employees have created the company’s success. As a result of that success, we are seeking individuals who enjoy a challenge and desire to be part of a team making a difference in healthcare outcomes. 

Position Summary

The Inside Tele-Sales Consultant (ITSC) will be primarily responsible for developing a pipeline of pre-qualified prospects. The ITSC manages inquiries by phone and/or web, identifies target accounts decision makers, sets up appointments for corporate field sales and reports results to. Will be required to proactively initiate and manage cold call activities into a target list of accounts, warm calls from trade show and other incoming lead sources. ITSC will provide primary sales follow up to OpGen’s install base to increase consumable usage. ITSC must be able to identify and qualify opportunities, build trust and credibility, deliver a clear and compelling message, uncover initiatives and gain commitment from prospect to engage with OpGen. Must be able to provide intermediate level of technical product support.

Primary Job Functions

• Target new opportunities and follow up on leads provided by marketing programs and tradeshows. Establish need, identify key contacts and decision-makers, qualify new products, and estimate budgetary resources available
• Manage consumable sales to global customer install base, establish standing orders and insure utilization is maximized
• Conduct outbound telephone prospecting based on lists of target customers provided by marketing with focus on MapIt Service
• Contact customers for purposes of data clean-up, contact discovery, event enrollment, reminder calls and other key activities
• Organization and prioritization of sales lead information into a CRM database
• Manage qualified lead and associated information flow in a succinct and efficient manner
• Analyze trends and buying patterns and communicates recommendations appropriately to management team
• Work closely with marketing and sales to ensure smooth and timely flow of information
• Maintain and increase technical product and application knowledge enabling you to provide prospective customers with compelling, accurate, and concise information about our products and prices over the telephone and basic level of technical product support
• Prepare customer quotations 

EDUCATION/SKILLS/ATTRIBUTES REQUIRED

• 1-2 years inside sales experience with a proven track record of success in Life Science or Diagnostics industries
• Must enjoy spending 90% of his/her time on the phone and embraces a creative challenge
• Must have a strong phone presence and interpersonal skills dealing with both internal and external clients, as well as prospects
• Must be customer service focused
• Demonstrated ability to handle objections and close sales
• Strong relationship building skills
• Ability to work as part of a team
• Positive attitude with ability to readily adapt to change
• Highly organized and attentive to details
• Excellent time management and prioritization skills

JOB RELATED KNOWLEDGE AND SKILLS 

• Customer focus – Is keenly in touch with customers’ needs; impeccable follow up with customers; and balances needs of customers with OpGen’s goals
• Leadership – Without prompting and coaching, takes initiative to communicate with, direct, and involve others to achieve goals; naturally guides, directs, or influences others; and conveys a positive attitude
• Sense of urgency – Acts with an independent sense of urgency to consistently develop and implement action plans to achieve goals and objectives.
• Team Oriented – Aligns team working toward common goals by leveraging strengths and providing vision.
• Personal Accountability – Readily takes complete ownership for successful attainment of all goals and tasks; never uses excuses if goal, task, or deadline is missed.
• Integrity – Acts ethically and honestly with external and internal customers
• Coachability & Self-Awareness – Has a clear understanding of her/his strengths and development areas; is open to feedback and integrates feedback into action; and understands impact of own behavior on teammates and customers.
• Communication Skills – Takes initiative to contact peers and share information, strategies, etc.; seeks out others and listens effectively; leverages consultative and interpersonal skills to articulate issues and needs to solve problems
• Business Acumen – Plans, communicates, and acts with a clear understanding of the business landscape; has a grasp of the customers organizational goals and operations as well as OpGen’s
• Possess strong oral and written communication skills and demonstrated fluency in presenting very technical material in a rapid paced environment
• Efficient time and territory management skills required. The geographic span of responsibilities is extensive.
• Limited travel to tradeshows, ability to carry minimum of 10 lbs. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. 

 Qualified applicants should submit a cover letter and resume to jobs@opgen.com indicating JOB CODE: ITSC in the subject heading. OpGen is an Equal Opportunity Employer. www.OpGen.com

OpGen Contact:
Judy Macemon
VP Marketing, OpGen, Inc.
(240) 813-1279

Gaithersburg, Md.—January 17, 2012— OpGen, Inc., a whole-genome analysis company developing and commercializing a complete suite of break-through products and services based on its proprietary Whole Genome Mapping technology, announced today that the company’s new Whole Genome Mapping and Genome Builder™ software was featured in a poster session at the International Plant & Animal Genome XX Conference, January 14-18, 2012 in San Diego.

The data, presented by researchers from the Beijing Forestry University, reported the significant progress made on the Chinese plum genome assembly. OpGen’s Argus® Whole Genome Mapping System and Genome-Builder software suite were utilized with sequencing data from the Beijing Genome Institute (BGI) to accurately close gaps in the genome sequence and improve genome assembly quality. The poster was presented by the principal author, Qixiang Zhang, Beijing Forestry University, on January 16, 2012.
Continuing advances in sequencing technologies and the decreasing cost of sequencing have resulted in vast amounts of data that must be assembled and analyzed. There is a growing backlog caused by the costly and time consuming bioinformatics and computing required to complete the assemblies and analysis. OpGen’s new applications and service can improve this process and enable a completed reference sequence in weeks, compared to months or years required by the current approaches.

In addition, OpGen will host a new technology workshop titled “Advances in Sequence Assembly and Structural Variation.” The workshop will feature presentations by Richard Moore, M.D., Ph.D., OpGen’s chief scientific officer, and Erin Newburn, Ph.D., an application scientist at OpGen. The workshop will provide an overview of the company’s new Genome-Builder software suite, which enables rapid, accurate sequence assembly and finishing of human, plant and animal genomes. The workshop will take place during the International Plant & Animal Genome XX Conference on January 17, 2012 from 3:50-6 p.m. PT in the Esquire room of the Town and Country Hotel.

“This is an exciting time for genomics research, and we are pleased to discuss how OpGen’s technology advancements can improve the efficiency and quality of sequence assembly and finishing for larger genomes,” said Dr. Moore. “Both the poster presentation and new technology workshop provide important forums for discussion of our findings and insights that enable closing 90 percent of the sequence gaps and providing a more comprehensive and complete view of genomes.”

About OpGen, Inc.
OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company’s Argus® Whole Genome Mapping System, GenomeBuilder® and MapIt® Services provide high resolution, whole genome maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. OpGen’s powerful technology dramatically improves the quality of data and time-to results by providing sequence information from single DNA molecules more rapidly and less expensively than previously possible. The company is dedicated to positively influencing individual healthcare outcomes, advancing scientific research and enhancing public health by delivering precise, actionable information and results to customers in the life science and healthcare communities. OpGen’s customers include leading genomic research centers, biodefense organizations, academic institutions, clinical research organizations and biotechnology companies. For more information, visit www.opgen.com.

Media Contant:
Dan Budwick
Pure Communications, Inc.
(973) 271-6085

OpGen Contact:
Judy Macemon
VP Marketing, OpGen, Inc.
(240) 813-1279 Contact:

Gaithersburg, Md.—December 20, 2011— OpGen, Inc., a whole-genome analysis company developing and commercializing a complete suite of break-through products and services based on its proprietary Whole Genome Mapping technology, announced today the appointment of Vadim Sapiro as chief information officer. In addition, the company announced the promotion and appointments of several key members of the executive committee. The organizational changes have been made to strengthen the management team and accelerate OpGen’s development and commercialization strategy. The company’s products enable rapid, accurate, high resolution whole genome analysis of microbes as well as more cost effective and accurate sequence assembly and finishing of human, animal, plant and microbial genomes.

“Vadim brings a wealth of knowledge and experience in information management and analysis to OpGen and will be focused on accelerating the commercialization of our portfolio of applications and tools for the sequence assembly, finishing and analysis markets,” said Doug White, chief executive officer of OpGen. “With the recent launch of our human, animal and plant sequencing applications in addition to our microbial whole genome mapping products, we will be expanding our capabilities to include web and cloud enabled analysis tools and databases. The recent management team appointments and promotions will positively position the company for commercial success and its next phase of growth.”

Mr. Sapiro joins OpGen’s management team as chief information officer and will be responsible for leading the development of OpGen’s bioinformatics applications, software, databases and information technology operations. Mr. Sapiro joins OpGen from SAIC-Frederick where he was senior vice president overseeing the Information Systems Program for the National Cancer Institute at Frederick with responsibility for information technology, scientific computing and bioinformatics. Among Mr. Sapiro’s projects were technical program management and operations for the cancer Biomedical Informatics Grid (caBIG™), the cancer Human Biobank (caHUB) and The Cancer Genome Atlas (TCGA). Prior to SAIC, Mr. Sapiro was vice president for information technology with the J. Craig Venter Institute. Mr. Sapiro is active in the regional and national technology and research communities, having served on many life sciences and biotech focused advisory boards and review committees. Mr. Sapiro holds a B.S. in mathematics and computer science from the University of Maryland. 

In addition to the hiring of Mr. Sapiro, the company announced the promotion of Richard Moore, Ph.D., MD, to chief scientific officer. In his new role, Dr. Moore will be responsible for leading the R&D organization and scientific collaborations with the genetics research, public health and clinical research communities. He joined OpGen as vice president of diagnostic systems in October 2008. Dr. Moore obtained an M.D. and a Ph.D. in cellular immunology from the University of Maryland at Baltimore and a B.S. in chemical and nuclear engineering from the University of Maryland, College Park.

Nick Stiso, Ph.D., was named vice president of manufacturing operations and is responsible for all manufacturing operations of OpGen’s Argus Whole Genome Mapping System, consumables and reagents kits. He brings more than 25 years of experience to OpGen with a strong track record in the development and management of successful manufacturing and support operations for life science systems and IVD products. Prior to joining OpGen, Dr. Stiso held executive level positions in development and manufacturing operations at Biosite Diagnostics, Accumetrics, Syva Co, GeneOhm Sciences and Miles Laboratories. Dr. Stiso earned a B.S. in chemistry from Georgetown University and a Ph.D. in physical chemistry from Michigan State University.

Judy Macemon was named vice president of marketing and is responsible for OpGen’s product portfolio management commercial strategies and tactics. Ms. Macemon brings 30 years of experience with a successful track record of leading commercial strategy development, building high performance marketing teams and global product launches in both the life science and clinical diagnostics markets. Before joining OpGen, Ms. Macemon was vice president of marketing at Helixis, Inc (now Illumina). Prior to Helixis, she held senior marketing roles at Life Technologies, Stratagene (now Agilent), MicroProbe and Becton Dickinson. Ms. Macemon has a B.S. in medical technology from Louisiana State University, M.S. in clinical microbiology from Texas Women’s University and M.B.A. from San Diego State University.

About OpGen, Inc.
OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company’s Argus^® Whole Genome Mapping System, GenomeBuilder^® and MapIt^® Services provide high resolution, whole genome maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. OpGen’s powerful technology dramatically improves the quality of data and time-to results by providing sequence information from single DNA molecules more rapidly and less expensively than previously possible. The company is dedicated to positively influencing individual healthcare outcomes, advancing scientific research and enhancing public health by delivering precise, actionable information and results to customers in the life science and healthcare communities. OpGen’s customers include leading genomic research centers, biodefense organizations, academic institutions, clinical research organizations and biotechnology companies. For more information, visit www.opgen.com.

Media Contact:
Dan Budwick
Pure Communications, Inc.
(973) 271-6085
dan@purecommunicationsinc.com

OpGen Contact:
Judy Macemon
VP Marketing, OpGen, Inc.
(240) 813-1279
ASHG Booth #1019

Gaithersburg, Md.—October 13, 2011— OpGen, Inc. announced today the launch of Genome-Builder, a high performance software module that provides new, powerful capabilities for precision sequence assembly and significantly decreases the time and labor required for human, animal and plant genome sequence assembly. OpGen presented initial studies using Genome-Builder this week with its collaborators at the Sanger Institute during a New Methods Workshop at the joint meeting of the American Society of Human Genetics (ASHG) and the International Congress of Human Genetics (ICHG) in Montreal.

“Genome-Builder expands the functionality of our Argus® Whole Genome Mapping System and provides a significant technology advancement for human genetics research that could lead to detecting clinically important rearrangements missed by current sequencing and array CGH approaches,” said Richard Moore, M.D., Ph.D., chief scientific officer at OpGen. “Using whole genome maps through Genome-Builder provides a high resolution, ordered visual map of the genomic architecture that will allow the detection of structural rearrangements at 10 times the resolution of traditional cytogenetic techniques. This more powerful capability can further help researchers identify important structural changes linked to a broad range of genetic diseases.”

By combining OpGen’s whole genome mapping technology with partially assembled sequences, Genome-Builder quickly and accurately orients long sequence scaffolds to provide a new level of assembly completion, saving the months of effort that can be required by current approaches. In addition, Genome-Builder works seamlessly with OpGen’s Argus Whole Genome Mapping System to enable the high resolution characterization and visual confirmation of very challenging repetitive regions that cannot be resolved by next generation sequencing or other currently available technologies.

Structure variation in human genomes is known to be pervasive, and studies have linked these positional and structural changes in genetic architecture to a number of genetic diseases including cancer, schizophrenia and autism. Despite recent advances in next generation sequencing and other technologies, the accurate detection and resolution of structural variation remains a significant challenge and prevents progress in expanding understanding of genetic disease.

“With the introduction of this new application, OpGen is now able to access and enable the human, animal and plant genome sequencing markets, significantly expanding the market potential for our technology,” said Doug White, chief executive officer of OpGen.   

About OpGen, Inc.
OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company has developed a platform, the Argus® Whole Genome Mapping System and also offers MapIt® Services that provide high resolution, whole genome restriction maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. This proprietary de novo technology is free from the limitations of gel, PCR and sequencing-based methodologies. Applications to expand whole genome mapping technology to clinical diagnostics are currently in development. OpGen’s customers include leading genomic research centers, biodefense organizations, academic institutions, clinical research organizations and biotechnology companies. For more information, visit www.opgen.com.

Media Contact:
Dan Budwick
Pure Communications, Inc.
(973) 271-6085
dan@purecommunicationsinc.com

OpGen Contact:
Judy Macemon
VP Marketing, OpGen, Inc.
(240) 813-1279

GAITHERSBURG, MD, October 11, 2011 – The Walter Reed Army Institute of Research (WRAIR) and OpGen, Inc. today announced publication of findings by the WRAIR that indicate a breakthrough in malaria research (Malaria Journal www.malariajournal.com/content/10/1/252).  Malaria affects over 250 million people, resulting in one million deaths each year and is considered a critical global health threat (WHO 2010 World Malaria Report). The team at WRAIR identified new areas of genetic variation in a multidrug-resistant malaria strain and reference sequence strains used in vaccine development, potentially identifying DNA associated with resistance and immune response. 

“Automated whole genome mapping technology allowed us to rapidly produce high quality optical maps that spanned all 14 chromosomes of four P.  falciparum genomes,” commented Captain Matthew Riley, chief of genomics for the Multidrug-resistant Organism Repository and Surveillance Network (MRSN).  “In addition, we identified new regions of interest in these malaria strains, including novel copy number variation that may be related to drug resistance, virulence factors and immune evasion.” The MRSN studies important pathogens to enhance performance improvement and focus infection control for U.S. military troops.

OpGen’s Argus® Whole Genome Mapping System provides rapid, accurate analysis of microbial genomes with complete, ordered, high-resolution DNA maps. The technology is widely used by public health labs and microbial researchers who study the emergence of disease outbreaks and hospital acquired infections that are increasingly difficult to treat with standard therapies.

“This study clearly demonstrates the practical application and value of combining OpGen’s Whole Genome Mapping capabilities with sequencing data to achieve high resolution genetic structure information required to identify important genomic regions associated with virulence and drug resistance,” commented Doug White, OpGen CEO. “DNA sequencing technologies are challenged with sorting out areas of genetic expansion and contraction, highly repetitive areas and locations in the genome where genes are presented in varying copy number from strain to strain. Whole Genome Mapping presents a clear picture of each genome’s architecture.”

About OpGen, Inc.
OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company developed the Argus® Whole Genome Mapping System and also offers MapIt™ Services that provide high resolution, whole genome DNA sequence maps and finished DNA sequence information. OpGen’s proprietary de novo technology has none of the limitations of sequencing-based methodologies, PCR or gels. The company’s technology is used by public health agencies and research labs worldwide to rapidly analyze microbial genomes, monitor disease outbreaks and emerging drug resistance. A new application of Whole Genome Mapping is also being applied large genome sequence improvement including mammals, vertebrates, humans and plants. OpGen’s customers include leading genomic research centers, biodefense organizations, academic institutions, clinical research organizations and biotechnology companies. For more information, visit www.opgen.com.

About WRAIR
The Walter Reed Army Institute of Research is the largest and oldest laboratory in the U.S. Army Medical Research and Material Command. It conducts research on a range of medical issues relevant to the military, including naturally occurring infectious diseases, operational health hazards (poor sleep and psychological health of Soldiers), and traumatic brain injury. For more information on new Centers of Excellence for Infectious Disease Research and Military Psychiatry and Neuroscience, visit www.wrair.army.mil.

Position Summary

As a member of our team, the Laboratory Associate will perform a variety of sample preparation and analysis procedures to produce whole genome physical maps from a wide range of bacteria. The Laboratory Associate will regularly perform data analysis for map assembly and initial quality testing using a wide range of Bioinformatics tools. The Laboratory Associate is expected to follow validated experimental procedures with occasional direct supervision from a group leader.

Primary Job Functions

• Prepare samples and perform tasks according to Company SOPs and cGMP guidelines.
• Perform high molecular weight DNA extraction from bacterial cells using microbiology and molecular biology methods.
• Maintain a laboratory notebook and complete all documentation according to Company SOPs.
• Communicate effectively and follow detailed written and verbal instruction.
• Cooperate with coworkers within an organized team environment and work.
• Manage time effectively to complete assignments in expected time frame.
• Perform work assignments accurately, timely and in a safe manner.
• Review and compile results from laboratory procedures.
• Effectively communicate project status to production leader.

Education/Skills/Attributes Required

• BS in molecular biology, microbiology, biochemistry, biology, chemistry or related discipline.
• Up to 2 years laboratory experience. Previous experience in a cGMP laboratory strongly desired.
• Ability to employ a broad range of skills including microbiology, molecular biology and/or bioinformatics.
• Flexibility to occasionally work varied hours.
• Ability to successfully interact with co-workers, vendors and customers.
• Knowledge of and ability to work in a chemical lab environment, which will require working with skin irritants, lung irritants, electrical equipment, sharp instruments, toxic materials, and hazardous waste. (Safety procedures will be followed to limit exposure.)
• Lifting/carrying objects of 5-15 lbs. on a weekly basis.
• Lifting/carrying objects of 16-50+ lbs. intermittently.
• Occasional kneeling and pushing/pulling of items.

Position Summary

As a member of our team, The Laboratory Assistant I – Manufacturing will perform a variety of procedures to produce product for sale as well as internal service business and R&D consumption. The Laboratory Assistant I – Manufacturing will be responsible for tracking process yields and participating in process improvement activities. The Laboratory Assistant I – Manufacturing is expected to follow validated procedures with occasional direct supervision from a group leader.

Primary Job Functions

• Manufacture product and perform tasks according to Company SOPs and cGMP guidelines
• Complete all documentation according to Company SOPs
• Recommend and participate in process improvement activities
• Communicate effectively and follow detailed written and verbal instructions
• Cooperate with coworkers within an organized team environment and work
• Manage time effectively to complete assignments in expected time frame
• Perform work assignments accurately and in a safe manner
• Effectively communicate project status to group leader

Education/Skills/Attributes Required

• High School Diploma with at least 1 year laboratory experience. Previous experience in a cGMP laboratory strongly desired.
• Prefer an Associate degree in molecular biology, microbiology, biochemistry, biology, chemistry or related discipline with at least 6 months laboratory experience.
• Ability to employ a range of skills including microbiology, molecular biology and/or bioinformatics.
• Ability to operate with limited supervision
• Strong teaming skills
• Adaptable to a rapidly changing environment
• Ability to learn quickly
• Ability to multitask
• Strong attention to detail
• Knowledge of and ability to work in a chemical lab environment, including use of standard laboratory equipment.
• With training, ability to use specialized equipment in the manufacture of product.
• General computer skills utilizing MS Office.
• Ability to communicate effectively, both in oral and written form with peers and management in the performance of the required duties.
• Basic mathematical skills required.
• SOP’s in place to ensure process
• Lifting/carrying objects of 5-15 lbs. on a daily basis.
• Lifting/carrying objects of 16-50+ lbs. at least weekly.
• Occasional kneeling and pushing/pulling of items.

OpGen, Inc. is a leading innovator in rapid, accurate genomic and DNA analysis systems and services. The company has developed a platform, The Argus™ Optical Mapping System and also offers MapIt™ Services that provide high resolution, whole genome restriction maps for sequence assembly and finishing, strain typing and comparative genomics in the life sciences market. This proprietary de novo technology is free from the limitations of gel, PCR and sequencing-based methodologies, and expansion of Optical Mapping technologies to large genomes and clinical diagnostics is currently in development. OpGen’s customers include leading genomic research centers, biodefense organizations, leading genomic research centers, academic institutions, clinical research organizations and biotechnology companies.

OpGen is committed to supporting our Customers as valued partners by creating long-term relationships and continually exceeding their expectations. OpGen employees have created the company’s success. As a result of that success, we are seeking individuals who enjoy a challenge and desire to be part of a team making a difference in healthcare outcomes.

Position Summary

We are seeking an experienced marketing professional for the position of Product Manager to support the commercial organization. Previous experience coordinating product development through launch is required, and both instrumentation and reagent experience is strongly desired. This individual would be expected to interact with customers and the sales force to drive demand for OpGen’s proprietary technology. Experience in sequencing is strongly preferred.

Primary Job Functions

• Develop and execute marketing tactics such as direct mail, advertising, customer seminars, e-marketing and, social media.
• Coordinate tradeshow plan to address target market segments, serve as point of contact for optimal execution and manage the lead generation and after show follow-up process.
• Maintain a highly effective and current web site.
• Develop marketing plans that are both strategic and involve tactical execution to achieve product awareness, demand creation and penetration into target markets.
• Coordinate cross functional team (R&D, production, QA, engineering) timeline to ensure on-time product launch.
• Work with internal research and development to ensure that products and services meet customer needs and requirements.
• Support the needs of the sales organization with effective sales tools, marketing collateral, product pricing and training.
• Maintain CRM system lead funnel, provide metrics to sales organization.

Education/Skills/Attributes Required

• BA / BS in Molecular Biology, Biochemistry or Biology, with MS or MBA preferred.
• 5-12 years experience in life science marketing, including product launch experience.
• Experience in the life science sequencing or genomics market strongly preferred.
• Strong verbal and written communication skills required with the ability to effectively articulate complex, technical information to a wide range of technical and non-technical audiences.
• Excellent interpersonal skills required. The ability to successfully interact with co-workers, customers and vendors is critical.
• Must be able to utilize appropriate techniques to analyze information and make sound technical and business decisions.
• Strong planning and organizing skills.
• Ability to multitask and appropriately prioritize.
• Requires some travel (35%), including international travel.