Using MapSolver™

View Your Whole Genome Maps

• Whole Genome Maps are visually displayed, showing genome-wide restriction cut sites
• Properties including the length of the map, total number of fragments, number of features, and number of alignments drawn to the map can be accessed
• Motifs can be easily identified, features annotated, and sequence data viewed from in silico maps

Compare Whole Genome Maps to Each Other, and to in silico Sequenced Genomes

• Whole or partial genome map comparisons between related organisms
• Similarities and differences highlighted and accessed for more detail: insertions, deletions, repetitive sequences, palindromes
• Features such as genes unique to the in silico map, not present in the Whole Genome Map, can be viewed using sequence annotation
• Searches can be performed for interesting unique restriction patterns, looking for regions of similarity
• Map-based clustering distinguishes strains and describes relatedness between mapped isolates

Place and Align Contigs, Enable Closure

• Sequence contig data can be uploaded into the database, allowing you to view your sequenced contigs
• Sequence contigs place on the Map where restriction patterns align to the Whole Genome Map—in less than a minute
• Inversions are easily viewed and can be corrected to correctly align the Map
• After contigs are aligned, gap size and location are visualized and can be determined
• Gap closure techniques, such as designing PCR primers, are easy and straightforward