Antibiotic Resistance Genotyping Analysis
Acuitas Whole Genome Sequencing analysis detects more than 2400 antibiotic resistance genes for evaluation of mechanisms and patterns of antibiotic resistance.
OpGen’s comprehensive and customized database identifies resistance gene subtypes for several classes of antibiotics including carbapenems, cephalosporins, penicillins, tetracyclines, macrolides, aminoglycosides, quinolones, sulfoxides and trimethoprim. Analysis is conducted on plasmid-mediated mechanisms of resistance such as beta-lactamases, AmpC genes and aminoglycoside modifying enzymes.
In addition, we also provide chromosomal determinants of resistance including gyrase A/parC genotypes and export pump/porin alterations.
Antibiotic Resistance Genotyping Analysis Workflow:
Submit bacterial isolate
Whole genome sequencing data generated
WGS Assembly and query against OpGen’s resistance gene database
Resistance gene report of the isolates delivered within 2 weeks.
Specimen Type: Single colony on bacterial slants. Download the Client Services Guide for sample preparation and shipping instructions.
Call 301.869.9683 or email to discuss your needs for Antibiotic Resistance Genotyping and Analysis.
The Acuitas Whole Genome Sequence Analysis tests are not CLIA validated by OpGen and are not for in vitro diagnostic use. Both tests are for research use only.